Retinal Thinning in People With Well-Controlled HIV Infection.

ABSTRACT:

Background

Retinal measurements correlate with disease progression in patients with multiple sclerosis; however, whether they associate with neurologic disease in people with controlled HIV is unknown. Using spectral domain optical coherence tomography, we evaluated retinal differences between people with HIV and HIV-negative controls and investigated clinical correlates of retinal thinning.

Methods

People with HIV on antiretroviral therapy for at least 1 year and HIV-negative controls recruited from the same communities underwent spectral domain optical coherence tomography, ophthalmic examination, brain MRI, and neuropsychological testing. Retinal nerve fiber layer (RNFL) and ganglion cell inner plexiform layer (GC-IPL) thicknesses were compared between groups using analys

SUBMITTER: Geannopoulos K 

PROVIDER: S-EPMC9475731 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature