Biocompatible Nanocapsules for Self-Healing Dental Resins and Bone Cements.

ABSTRACT: Bone cements and dental resins are methacrylate-based materials that have been in use for many years, but their failure rates are quite high with essentially all dental resins failing within 10 years and 25% of all prosthetic implants will undergo aseptic loosening. There are significant healthcare costs and impacts on quality of life of patients. Self-healing bone cements and resins could improve the lifespan of these systems, reduce costs, and improve patient outcomes, but they have been limited by efficacy and toxicity of the components. To address these issues, we developed a self-healing system based on a dual nanocapsule system. Two nanocapsules were synthesized, one containing an initiator and one encapsulating a monomer, both in polyurethane shells. The monomer used was triethylene

SUBMITTER: Menikheim S 

PROVIDER: S-EPMC9476208 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature