Blood pressure in children with sickle cell disease is higher than in the general pediatric population.

ABSTRACT:

Background

Sickle cell disease (SCD) is associated with an increased risk of cardiovascular disease that may be due to a variety of possible risk factors, including abnormal blood pressure. Blood pressure (BP) of children and adolescents with SCD has been reported to be lower compared to the BP of the general pediatric population.

Methods

To confirm this prior observation, we compared reference BP values for children with SCD with reference BP values of the general pediatric population. We hypothesized that children with SCD do not have lower BPs than children without SCD.

Results

Systolic BP differed for both males and females, over the different age groups between pediatric subjects with and without SCD. Systolic BP was higher in children with SCD, in both obese and

SUBMITTER: Kupferman JC 

PROVIDER: S-EPMC9476310 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature