In-hospital clinical outcomes in diffusion weighted imaging-negative stroke treated with intravenous thrombolysis.

ABSTRACT:

Objective

We aimed to investigate whether negative diffusion weighted imaging (DWI) is related to the in-hospital clinical outcomes for ischemic stroke patients with intravenous tissues plasminogen activator (IV tPA).

Methods

We retrospectively enrolled patients who received IV tPA therapy within 4.5 hours from symptoms onset. The classification of DWI-positive or negative was based on post-IV tPA MR scan. Demographic factors, stroke characteristics, imaging information, and the in-hospital clinical outcomes including early neurological improvement (ENI) and favourable functional outcome were collected. Multivariable logistic regression and sensitivity analyses were conducted to test whether negative DWI imaging was an independent predictor of the in-hospital clinical outcom

SUBMITTER: Li G 

PROVIDER: S-EPMC9476428 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature