Molecular mechanism of Chuanxiong Rhizoma in treating coronary artery diseases.

ABSTRACT:

Objective

Most of the studies on the herb Chuanxiong Rhizoma (CR) have focused on the l-arginine-nitric oxide (NO) pathway, but the nitrate-nitrite-NO (NO₃ ^--NO₂ ^--NO) pathway was rarely investigated. Therefore, the aim of this study was to evaluate the effects and mechanisms of action of CR in coronary artery disease (CAD).

Methods

The NO₃ ^-, NO₂ ^- and NO levels were examined in the NO₃ ^--NO₂ ^--NO pathway. High-performance ion chromatography was used to quantify NO₃ ^- and NO₂ ^- levels. Then, NO was quantified using a multifunctional enzyme marker with a fluorescent probe. The tension of

SUBMITTER: Yin BQ 

PROVIDER: S-EPMC9476474 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature