Ag@TiO₂ Nanocomposite as an Efficient Catalyst for Knoevenagel Condensation.

ABSTRACT: In the present study, a new series of different heterocycles was synthesized through base-free Knoevenagel condensation of various aldehydes and active methylene-containing compounds using the hydrothermal developed Ag@TiO₂ as a heterogeneous catalyst. The catalyst was synthesized by mixing TiO₂ (P25) with AgNO₃ and hydrothermally treated in ethanol at 180 °C for 12 h. The developed Ag@TiO₂ catalyst was directly applied for Knoevenagel condensation, and the optimized procedure involved stirring the aldehydes and active methylene-containing compounds with Ag@TiO₂ in ethanol at 65 °C. The reaction scope was investigated for various aromatic and heterocyclic aldehydes with active methylene-containing compounds, and the isolated yields wer

SUBMITTER: Sayed M 

PROVIDER: S-EPMC9476541 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature