Peroral endoscopic myotomy vs laparoscopic myotomy and partial fundoplication for esophageal achalasia: A single-center randomized controlled trial.

ABSTRACT:

Background

Achalasia is a rare benign esophageal motor disorder characterized by incomplete relaxation of the lower esophageal sphincter (LES). The treatment of achalasia is not curative, but rather is aimed at reducing LES pressure. In patients who have failed noninvasive therapy, surgery should be considered. Myotomy with partial fundoplication has been considered the first-line treatment for non-advanced achalasia. Recently, peroral endoscopic myotomy (POEM), a technique that employs the principles of submucosal endoscopy to perform the equivalent of a surgical myotomy, has emerged as a promising minimally invasive technique for the management of this condition.

Aim

To compare POEM and laparoscopic myotomy and partial fundoplication (LM-PF) regarding their efficacy and ou

SUBMITTER: de Moura ETH 

PROVIDER: S-EPMC9476850 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature