Melamine-derived N-rich C-entrapped Au nanoparticles for sensitive and selective monitoring of dopamine in blood samples.

ABSTRACT: Several neurological disorders, including Parkinson's disease, schizophrenia, human immunodeficiency virus infection, and restless leg syndrome, majorly result from disruption in the dopamine (DA) level. Thus, useful information about the treatment and prevention of various genetic majorly mental health problems can be obtained through precise and real-time monitoring of DA. Herein, we report the fabrication of novel N-rich carbon-coated Au nanoparticles (NC@Au-NPs) by deriving from melamine-crosslinked citrate-stabilized Au NPs. NC@Au-NPs offer fast electro-oxidation efficacy towards DA, because of strong electrostatic attraction between negatively charged NC@Au-NPs and positively charged DA. The catalytic efficacy and shelf life of the designed system were further boosted by applying a m

SUBMITTER: Shakeel F 

PROVIDER: S-EPMC9477018 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature