Evaluation of Efficacy of Adjuvant Radiotherapy in Well-Differentiated Liposarcoma Patients with Positive Surgical Margins: A Population-based Study.

ABSTRACT:

Background

The use of adjuvant radiotherapy (RT) for well-differentiated liposarcoma (WD-LPS) patients with positive surgical margins is unclear. We aim to compare the overall survival (OS) and cancer-specific survival (CSS) of well-differentiated liposarcoma patients with positive surgical margins in an RT group and non-RT group.

Methods

WD-LPS patients with positive margins from 2000 to 2018 were extracted from the Surveillance, Epidemiology, and End Results (SEER) database and divided into two groups: RT group and non-RT group. Kaplan-Meier survival analysis with the log-rank test was performed to evaluate the difference of overall survival (OS) and cancer-specific survival (CSS) between groups. Univariate and multivariate Cox proportional hazard analyses were performed t

SUBMITTER: Wang H 

PROVIDER: S-EPMC9477581 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature