Efficacy and Safety of Gegen Qinlian Decoction for Pediatric Diarrhea: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objective

To evaluate the clinical efficacy and safety of Gegen Qinlian decoction in the treatment of pediatric diarrhea.

Methods

A search for relevant RCTs was performed from which a systematic review and meta-analysis was conducted. This meta-analysis was registered at INPLASY (reference number ID: INPLASY202180105).

Results

(1) Eleven trials involving 1126 patients were included in the meta-analysis. (2) Two trials recorded the adverse events. (3) The meta-analysis showed that compared with the control group, the experimental group has a significantly shorter duration of diarrhea in children (MD = -18.64, 95% CI (-23.76, -13.52), P < 0.00001), duration of fever (MD = -19.43, 95% CI (-25.76, -13.11), P < 0.00001), duration of vomiting [MD = -22.51, 95%

SUBMITTER: Wang D 

PROVIDER: S-EPMC9477636 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature