Retinal microvascular associations with cardiometabolic risk factors differ by diabetes status: results from the UK Biobank.

ABSTRACT:

Aims/hypothesis

The aim of the study was to examine the association of retinal vessel morphometry with BP, body composition and biochemistry, and to determine whether these associations differ by diabetes status.

Methods

The UK Biobank ocular assessment included 68,550 participants aged 40-70 years who underwent non-mydriatic retinal photography, BP and body composition measurements, and haematological analysis. A fully automated image analysis program provided measurements of retinal vessel diameter and tortuosity. The associations between retinal vessel morphology and cardiometabolic risk factors by diabetes status were examined using multilevel linear regression, to provide absolute differences in vessel diameter and percentage differences in tortuosity (allowing for with

SUBMITTER: Tapp RJ 

PROVIDER: S-EPMC9477904 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature