Clinical outcomes of adults and children with cystic fibrosis during the COVID-19 pandemic.

ABSTRACT:

Background

The onset of the COVID-19 pandemic was associated with restricted community movement and limited access to healthcare facilities, resulting in changed clinical service delivery to people with cystic fibrosis (CF). This study aimed to determine clinical outcomes of Australian adults and children with CF in the 12-months following the onset of the COVID-19 pandemic.

Methods

This longitudinal cohort study used national registry data. Primary outcomes were 12-month change in percent predicted forced expiratory volume in one second (FEV1 %pred), body mass index (BMI) in adults and BMI z-scores in children. A piecewise linear mixed-effects model was used to determine trends in outcomes before and after pandemic onset.

Results

Data were available for 3662 individu

SUBMITTER: Doumit M 

PROVIDER: S-EPMC9477965 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature