Trends in clinical characteristics and factors associated with initial prescription of SGLT2 inhibitors in Japanese patients with type 2 diabetes mellitus.

ABSTRACT:

Aims

To investigate the changes in patient background and treatment lines between 2016-2019 and contributing factors when sodium-glucose co-transporter 2 inhibitors (SGLT2i) are newly prescribed for type 2 diabetes mellitus patients.

Methods

The subjects comprised patients who had attended outpatient clinics at the four Jikei University School of Medicine-affiliated hospitals. One-way analysis of variance was used to evaluate annual changes in patients' characteristics. Logistic regression analysis was also used to explore factors contributing to the treatment lines.

Results

The age of the 1951 subjects [mean ± SD] was 59.1 ± 12.8 years; BMI 27.5 ± 4.9 kg/m²; HbA1c 8.15 ± 1.24%; eGFR 74.2 ± 25.3 ml/min/1.73m². SGLT2i was the 2.86th (± 1.22) new p

SUBMITTER: Takahashi H 

PROVIDER: S-EPMC9477997 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature