Pediatric eosinophilic esophagitis outcomes vary with co-morbid eczema and pollen food syndrome.

ABSTRACT:

Background

Eosinophilic esophagitis (EoE) is a chronic immune-mediated inflammatory disease characterized by eosinophil inflammation of the esophagus. It has been described as a component of the Allergic March and is often seen with other atopic diseases. Some atopic diseases, including asthma, are known to be heterogenous with endotypes that guide treatment. Similarly, we propose that EoE is a heterogenous disease with varying phenotypes and endotypes that might impact response to therapy.

Methods

A single-center retrospective review of pediatric patients ≤18 years of age diagnosed with EoE was conducted. All gastrointestinal clinic visits and esophagogastroduodenoscopies (EGD) from disease presentation through the first three years after diagnosis were reviewed. Histologic

SUBMITTER: Sessions J 

PROVIDER: S-EPMC9478188 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature