Research into the mechanism of intervention of SanQi in endometriosis based on network pharmacology and molecular docking technology.

ABSTRACT:

Background

By using network pharmacology and molecular docking technology, we have explored the mechanism of action of Sanqi in the treatment of endometriosis (EMS), in order to provide reference for clinical studies of Chinese medicine treatment of Ems and Chinese medicine pharmacology.

Methods

There are 123 intersecting targets between the active ingredients of Sanqi and disease targets. In the Protein-Protein Interaction network, Jun proto-oncogene, AP-1 transcription factor subunit, tumor necrosis factor, interleukin 6, etc., are the core proteins. The top 20 genes ranked by degree have been analyzed according to the Kyoto Encyclopedia of Genes and Genomes pathway and Gene Ontology analysis, and 20 pathways have been identified.

Results

On the Kyoto Encyclopedia o

SUBMITTER: Lin Z 

PROVIDER: S-EPMC9478308 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature