Paternal Occupation and Delirium Risk in Older Adults: A Potential Marker of Early-Life Exposures.

ABSTRACT:

Background and objectives

Delirium is a common disorder among older adults following hospitalization or major surgery. Whereas many studies examine the risk of proximate exposures and comorbidities, little is known about pathways linking childhood exposures to later-life delirium. In this study, we explored the association between paternal occupation and delirium risk.

Research design and methods

A prospective observational cohort study of 528 older adults undergoing elective surgery at two academic medical centers. Paternal occupation group (white collar vs. blue collar) served as our independent variable. Delirium incidence was assessed using the Confusion Assessment Method (CAM) supplemented by medical chart review. Delirium severity was measured using the peak CAM-Severi

SUBMITTER: Shiff HM 

PROVIDER: S-EPMC9478553 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature