Lactobacillus acidophilus novel strain, MJCD175, as a potential probiotic for oral health in dogs.

ABSTRACT: The oral cavity is the second-largest habitat for microorganisms, and a well-balanced oral microbiome contributes to preventing dental disorders caused by pathogenic bacteria. Since humans and dogs have different lifestyles and oral microbiome structures, the present study aimed to develop novel probiotics for dogs. A total 53 Lactobacillus spp. were isolated from healthy dogs, and nine isolates were identified as Lactobacillus acidophilus according to 16S rRNA gene sequencing. According to the high antimicrobial activity against the dental caries-causing bacterium Streptococcus mutans, single or three mixed strains were orally administered to dogs for 4 weeks with concentration of 10⁸-10⁹ CFU/day. Intraoral swab samples were collected before and

SUBMITTER: You I 

PROVIDER: S-EPMC9478757 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature