Ontology highlight
ABSTRACT: Objectives
This study was designed to evaluate the effect of rehabilitation in preventing decreased functional status (FS) after community-acquired pneumonia (CAP) in elderly patients.Design
This was a retrospective observational study.Setting
Multicentre study was conducted in two medical facilities from January 2016 to December 2018.Participants
Hospitalised patients with CAP aged over 64 years were enrolled. FS was assessed by the Barthel Index (BI) (range, 0-100, in 5-point increments) at admission and before discharge and graded into three categories: independent, BI 80-100; semidependent, BI 30-75; and dependent, BI 0-25. Multivariable analysis of factors contributing to decreased FS was conducted with two groups: with a decrease of at least one category (decreased group) or without a decrease of category (maintained group).Primary and secondary outcome measures
The primary outcome was the effect of rehabilitation in preventing decreased FS. The secondary outcomes were factors associated with decreased FS.Results
The maintained and decreased groups included 400 and 138 patients, respectively. A high frequency of rehabilitation therapy was observed in the decreased group (189 (47.3%) vs 104 (75.4%); p<0.001). Multivariable analysis showed that the factors affecting FS were aspiration pneumonia, Pneumonia Severity Index (PSI) category V, length of stay and age (OR 2.66, 95% CI 1.58 to 4.49; OR 1.92, 95% CI 1.29 to 3.44; OR 1.05, 95% CI 1.04 to 1.07; and OR 1.05, 95% CI 1.02 to 1.09, respectively). After adjusting for factors contributing to decreased FS, rehabilitation showed a limited effect in preventing decreased FS in 166 matched pairs by McNemar's test (p=0.327).Conclusions
Aspiration and PSI played important roles in reducing FS. The effect of rehabilitation remains unclear in CAP.Trial registration number
UMIN000046362.
SUBMITTER: Chen H
PROVIDER: S-EPMC9478837 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
Chen Hao H Hara Yu Y Horita Nobuyuki N Saigusa Yusuke Y Hirai Yoshihiro Y Kaneko Takeshi T
BMJ open 20220915 9
<h4>Objectives</h4>This study was designed to evaluate the effect of rehabilitation in preventing decreased functional status (FS) after community-acquired pneumonia (CAP) in elderly patients.<h4>Design</h4>This was a retrospective observational study.<h4>Setting</h4>Multicentre study was conducted in two medical facilities from January 2016 to December 2018.<h4>Participants</h4>Hospitalised patients with CAP aged over 64 years were enrolled. FS was assessed by the Barthel Index (BI) (range, 0-1 ...[more]