Default mode and fronto-parietal network associations with IQ development across childhood in autism.

ABSTRACT:

Background

Intellectual disability affects approximately one third of individuals with autism spectrum disorder (autism). Yet, a major unresolved neurobiological question is what differentiates autistic individuals with and without intellectual disability. Intelligence quotients (IQs) are highly variable during childhood. We previously identified three subgroups of autistic children with different trajectories of intellectual development from early (2-3½ years) to middle childhood (9-12 years): (a) persistently high: individuals whose IQs remained in the normal range; (b) persistently low: individuals whose IQs remained in the range of intellectual disability (IQ < 70); and (c) changers: individuals whose IQs began in the range of intellectual disability but increased to the normal

SUBMITTER: Lee JK 

PROVIDER: S-EPMC9479280 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature