Potential role of tea drinking in preventing hyperuricaemia in rats: biochemical and molecular evidence.

ABSTRACT:

Background

Lifestyle and diet play a significant role in hyperuricaemia. Accumulating evidence indicates that tea consumption is associated with hyperuricaemia and gout. However, diverse compounds in different types of tea make it quite difficult to determine the relevant molecular mechanism. Here, we compared the effects of six types of tea on hyperuricaemia induced by potassium oxonate (PO) and hypoxanthine in rats and investigated the possible underlying mechanisms.

Methods

Rats were randomly assigned to ten groups: the control, hyperuricaemia model, benzbromarone positive control, traditional Chinese medicine Simiao San positive control, green tea, yellow tea, black tea, white tea, red tea, and cyan tea treatment groups. After 21 days, uric acid (UA), xanthine oxidase (X

SUBMITTER: Sang S 

PROVIDER: S-EPMC9479443 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature