Performance of urinary liver-type fatty acid-binding protein in diabetic nephropathy: A meta-analysis.

ABSTRACT:

Aims

Diabetic nephropathy (DN) is one of the main causes of chronic kidney disease (CKD), which increases the risk of cardiovascular diseases and progresses to end-stage renal failure. Thus, early diagnostic markers for diabetic patients are urgently needed to improve the prognosis of DN and predict DN progression.

Materials and methods

PubMed, MEDLINE, EMBASE, and Scopus were searched for publications until February 24, 2021. Review Manager 5.4 software was used for meta-analysis. We performed the heterogeneity test using the I² statistic: P < 0.1 and I²> 50% meant statistical significance.

Results

We included 13 studies. The urinary liver-type fatty acid-binding protein (uL-FABP) concentrations in the normal albuminuria group were signif

SUBMITTER: Zhang L 

PROVIDER: S-EPMC9479543 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature