Hepatitis E - epidemiology and clinical course in the largest cohort in the Czech Republic.

ABSTRACT:

Introduction

The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic.

Methods

A retrospective analysis of 173 patients with HE.

Results

At least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE.

Conclusions

There is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic.

SUBMITTER: Mihalcin M 

PROVIDER: S-EPMC9479705 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature