SARS-CoV-2 and post-donation information: a one-year experience of the French haemovigilance network.

ABSTRACT:

Background

There is growing evidence to support the hypothesis that SARS-CoV-2 is probably not transmissible by blood transfusion. In this study, we use the data gathered over one year by the French haemovigilance network on post-donation information related to SARS-CoV-2, and virological investigations on corresponding plasma to explore viral transmission by transfusion.

Materials and methods

Whenever a donor reported COVID-19 symptoms and/or a positive SARS-CoV-2 nasopharyngeal (NP) PCR test, information regarding diagnosis and symptoms was collected using a specific questionnaire, and repository plasmas were screened using the SARS-COV-2 R-GENE^® assay (Biomérieux). RNA sequencing (Sanger and deep sequencing) and virus isolation on Vero E6 cells were applied in

SUBMITTER: Cappy P 

PROVIDER: S-EPMC9480969 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature