Strongyloides stercoralis infection induces gut dysbiosis in chronic kidney disease patients.

ABSTRACT:

Background

Strongyloides stercoralis infection typically causes severe symptoms in immunocompromised patients. This infection can also alter the gut microbiota and is often found in areas where chronic kidney disease (CKD) is common. However, the relationship between S. stercoralis and the gut microbiome in chronic kidney disease (CKD) is not understood fully. Recent studies have shown that gut dysbiosis plays an important role in the progression of CKD. Hence, this study aims to investigate the association of S. stercoralis infection and gut microbiome in CKD patients.

Methodology/principal findings

Among 838 volunteers from Khon Kaen Province, northeastern Thailand, 40 subjects with CKD were enrolled and divided into two groups (S. stercoralis-infected and -uninfected) mat

SUBMITTER: Hai NT 

PROVIDER: S-EPMC9481163 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature