Contribution of behavioural variability to representational drift.

ABSTRACT: Neuronal responses to similar stimuli change dynamically over time, raising the question of how internal representations can provide a stable substrate for neural coding. Recent work has suggested a large degree of drift in neural representations even in sensory cortices, which are believed to store stable representations of the external world. While the drift of these representations is mostly characterized in relation to external stimuli, the behavioural state of the animal (for instance, the level of arousal) is also known to strongly modulate the neural activity. We therefore asked how the variability of such modulatory mechanisms can contribute to representational changes. We analysed large-scale recording of neural activity from the Allen Brain Observatory, which was used before to d

SUBMITTER: Sadeh S 

PROVIDER: S-EPMC9481246 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature