Non-targeted analysis with high-resolution mass spectrometry for investigation of riverbank filtration processes.

ABSTRACT: A fully non-targeted analytical workflow for the investigation of a riverbank filtration site located at the river Danube has been developed and applied. Variations of compound intensities at different sampling locations of the riverbank filtration site and, for a single production well, over a monitoring period of one year have been investigated using liquid chromatography combined with time-of-flight-mass spectrometry followed by evaluation via non-targeted data analysis. Internal standardization and appropriate quality control strategies have been implemented into the workflow for reduction of possible methodological biases influencing data interpretation. Emphasis was placed on the assessment of different blank elimination steps and the final blank elimination strategy is reported. The

SUBMITTER: Kutlucinar KG 

PROVIDER: S-EPMC9481508 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature