Child maltreatment, anxiety and depression, and asthma among British adults in the UK Biobank.

ABSTRACT:

Background

Child maltreatment is associated with asthma in adults. We examined whether lifetime major depressive disorder (MDD) or lifetime generalised anxiety disorder (GAD) mediate an association between child maltreatment and current asthma among 81 105 British adults in the UK Biobank who completed a mental health survey and had complete data on child maltreatment, GAD, MDD, asthma and relevant covariates but no diagnosis of chronic obstructive pulmonary disease.

Methods

Child maltreatment was ascertained based on answers to the five questions in the Childhood Trauma Screener. Two mediators, lifetime MDD and GAD, were assessed based on the Composite International Diagnostic Interview Short Form. Current asthma was defined as physician-diagnosed asthma and wheeze or whist

SUBMITTER: Han YY 

PROVIDER: S-EPMC9481745 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature