Pharmacodynamic determinants of hangover: An intravenous alcohol self-administration study in non-dependent drinkers.

ABSTRACT: Alcohol hangover refers to the combination of negative mental and physical symptoms that can be experienced after an episode of alcohol consumption, typically emerging as blood alcohol concentration (BAC) approaches zero. Hangover has been associated with heavy drinking and may be relevant in the transition to alcohol use disorder (AUD). Our aim was to examine hangover prevalence and associated symptoms following intravenous alcohol self-administration (IV-ASA), and to identify possible predictors of hangover in non-dependent drinkers. Ninety-five drinkers without AUD completed an IV-ASA session. Pharmacodynamic measures of alcohol consumption included peak and average breath alcohol concentrations. Subjective measures of alcohol response included the Drug Effects Questionnaire and Biphasi

SUBMITTER: Stangl BL 

PROVIDER: S-EPMC9482023 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature