Quantitative and qualitative characterization of commercially available oral suspension of probiotic products containing Bacillus Clausii spores.

ABSTRACT: Probiotics contain beneficial live bacteria that confer several health benefits to the host. For the past 50 years, spore-forming Bacillus species have been used in the form of probiotics. Among these, Bacillus clausii strains are used for the management of acute and antibiotic-associated diarrhoea. In the present work, we have evaluated the asserted label information on randomly chosen commercial Bacillus clausii spore suspension of probiotic products. The quality and number of viable bacteria were evaluated based on the colony count, antibiotic resistance, and hemolytic activity assays. The colony fingerprinting and 16S rRNA gene-sequencing techniques were used to confirm the presence of a univariate strain (Bacillus clausii). Our results corroborated the label count of 2 × 10⁹

SUBMITTER: Kharwar A 

PROVIDER: S-EPMC9482283 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature