Clostridioides difficile Infection in a Japanese Tertiary Children's Hospital.

ABSTRACT:

Purpose

Toxins produced by Clostridioides difficile infection (CDI) can cause enteritis and diarrhea. Although the number of pediatric CDI cases is increasing, the clinical management of pediatric CDI, including patient characteristics and prognosis, remains unclear. This study aimed to elucidate the background and clinical course of patients with CDI and evaluate the reliability of diagnostic tests in a tertiary pediatric hospital in Japan.

Methods

We retrospectively analyzed the clinical data of children diagnosed with CDI between 2011 and 2021 at the Saitama Children's Medical Center in Saitama, Japan.

Results

During the study period, 1,252 C. difficile antigen/toxin tests were performed, and 37 patients were diagnosed with CDI. The main underlying di

SUBMITTER: Meguro M 

PROVIDER: S-EPMC9482825 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature