Functional recovery after accidental deep hypothermic cardiac arrest: Comparison of different cardiopulmonary bypass rewarming strategies.

ABSTRACT: Introduction: Using a porcine model of accidental immersion hypothermia and hypothermic cardiac arrest (HCA), the aim of the present study was to compare effects of different rewarming strategies on CPB on need for vascular fluid supply, level of cardiac restitution, and cerebral metabolism and pressures. Materials and Methods: Totally sixteen healthy, anesthetized castrated male pigs were immersion cooled to 20°C to induce HCA, maintained for 75 min and then randomized into two groups: 1) animals receiving CPB rewarming to 30°C followed by immersion rewarming to 36°C (CPB₃₀, n = 8), or 2) animals receiving CPB rewarming to 36°C (CPB₃₆, n = 8). Measurements of cerebral metabolism were collected using a microdialysis catheter. After rewarmin

SUBMITTER: Filseth OM 

PROVIDER: S-EPMC9483155 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature