Reward sensitivity modulates the brain reward pathway in stress resilience via the inherent neuroendocrine system.

ABSTRACT: In the previous 10 years, researchers have suggested a critical role for the brain reward system in stress resilience. However, no study has provided an empirical link between activity in the mesostriatal reward regions during stress and the recovery of cortisol stress response. Moreover, although reward sensitivity as a trait has been demonstrated to promote stress resilience, it remains unclear whether it modulates the brain reward system in stress resilience and how this effect is achieved by the inherent neuroendocrine system. To investigate these uncertainties, 70 young adults were recruited to participate in a ScanSTRESS task, and their brain imaging data and saliva samples (for cortisol assay) were collected during the task. In addition, we assessed reward sensitivity, cortis

SUBMITTER: Hu W 

PROVIDER: S-EPMC9483565 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature