Prognosis stratification and postoperative radiation therapy utilization in adenoid cystic carcinoma of the breast.

ABSTRACT:

Purpose

Adenoid cystic carcinoma of the breast (ACCB) is a rare malignancy with a favorable prognosis. Little information exists regarding the impact of postoperative radiation therapy (RT) on survival outcome in patients with ACCB. This study aimed to evaluate the clinical significance of postoperative RT in ACCB.

Methods

Data of patients with ACCB were extracted from the Surveillance, Epidemiology, and End Results database (2000-2019). Univariate and multivariable Cox regression analyses were performed to identify prognostic factors. In addition, a nomogram model was constructed and internally validated for discrimination and calibration. The value of postoperative RT was respectively accessed in each risk subgroup according to nomogram-deduced individualized score.

Res

SUBMITTER: Zhang D 

PROVIDER: S-EPMC9483639 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature