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Correlation between cow's milk protein allergy and otitis media: a systematic review.


ABSTRACT:

Objectives

To review the evidence pertaining to the association between cow's milk protein allergy and recurrent acute otitis media and otitis media with effusion.

Methods

The CENTRAL, Web of Science, EMBASE, MEDLINE, LILACS databases, and gray literature were searched.

Results

Four studies were included, identifying the prevalence rates: 0.2% of delayed speech due to chronic otitis media with effusion in 382 children with cow's milk protein allergy, 10.7% of cow's milk protein allergy in 242 children who underwent ENT procedures, 40% of cow's milk protein allergy in 25 children with recurrent otitis media with effusion and higher tendency to otitis media in children with cow's milk protein allergy of 186 children (1.5 + 0.6 vs. 0.4 + 0.1; p < 0.1).

Conclusion

Considering the characteristics and methodological variations of the identified studies, it is not possible to state that there is reliable evidence of an association between cow's milk protein allergy and otitis media.

SUBMITTER: Oliveira KAS 

PROVIDER: S-EPMC9483997 | biostudies-literature | 2022 Sep-Oct

REPOSITORIES: biostudies-literature

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Correlation between cow's milk protein allergy and otitis media: a systematic review.

Oliveira Karen Amanda Soares de KAS   Esper Marina Tomaz MT   Oliveira Morgana Lívia de ML   Tofoli Marise Helena Cardoso MHC   Avelino Melissa Ameloti Gomes MAG  

Brazilian journal of otorhinolaryngology 20211018 5


<h4>Objectives</h4>To review the evidence pertaining to the association between cow's milk protein allergy and recurrent acute otitis media and otitis media with effusion.<h4>Methods</h4>The CENTRAL, Web of Science, EMBASE, MEDLINE, LILACS databases, and gray literature were searched.<h4>Results</h4>Four studies were included, identifying the prevalence rates: 0.2% of delayed speech due to chronic otitis media with effusion in 382 children with cow's milk protein allergy, 10.7% of cow's milk pro  ...[more]

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