Counting the cost of premature mortality with progressively worse aortic stenosis in Australia: a clinical cohort study.

ABSTRACT:

Background

Aortic stenosis is the most common cardiac valve disorder requiring clinical management. However, there is little evidence on the societal cost of progressive aortic stenosis. We sought to quantify the societal burden of premature mortality associated with progressively worse aortic stenosis.

Methods

In this observational clinical cohort study, we examined echocardiograms on native aortic valves of 98 565 men and 99 357 women aged 65 years or older across 23 sites in Australia, from Jan 1, 2003, to Dec 31, 2017. Individuals were grouped according to their peak aortic valve velocity in 0·50 m/s increments up to 4·00 m/s or more (severe aortic stenosis), using 1·00-1·99 m/s (no aortic stenosis) as the reference group. Sex-specific premature mortality and years of li

SUBMITTER: Stewart S 

PROVIDER: S-EPMC9484033 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature