Precision Medicine Approach to Alzheimer's Disease: Successful Pilot Project.

ABSTRACT:

Background

Effective therapeutics for Alzheimer's disease are needed. However, previous clinical trials have pre-determined a single treatment modality, such as a drug candidate or therapeutic procedure, which may be unrelated to the primary drivers of the neurodegenerative process. Therefore, increasing data set size to include the potential contributors to cognitive decline for each patient, and addressing the identified potential contributors, may represent a more effective strategy.

Objective

To determine whether a precision medicine approach to Alzheimer's disease and mild cognitive impairment is effective enough in a proof-of-concept trial to warrant a larger, randomized, controlled clinical trial.

Methods

Twenty-five patients with dementia or mild cognitive imp

SUBMITTER: Toups K 

PROVIDER: S-EPMC9484109 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature