Genetic Testing and Hospital Length of Stay in Neonates With Epilepsy.

ABSTRACT:

Background

We evaluated changes in genetic testing for neonatal-onset epilepsy and associated short-term outcomes over an 8-year period among a cohort of patients in the neonatal intensive care unit (NICU) at a single institution before and after the introduction of sponsored genetic epilepsy testing in January 2018.

Methods

Our primary outcome was a change in length of stay (LOS) after 2018. We also ascertained severity of illness with the Neonatal Sequential Organ Failure Assessment (nSOFA), type and result of genetic testing, turnaround time to molecular diagnosis (TAT), LOS, antiseizure medications (ASMs), and use of technology at discharge. We compared outcomes using nonparametric tests and difference-in-difference analysis.

Results

Fifty-three infants with genet

SUBMITTER: Akbari H 

PROVIDER: S-EPMC9484310 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature