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Effects of L-carnitine supplementation for women with polycystic ovary syndrome: a systematic review and meta-analysis.


ABSTRACT:

Background

Polycystic ovary syndrome (PCOS) is a disorder in reproductive age women and is characterized by hyperandrogenic anovulation and oligo-amenorrhea, which leads to infertility. Anovulation in PCOS is associated with low follicle-stimulating hormone levels and the arrest of antral follicle development in the final stages of maturation. L-carnitine (LC) plays a role in fatty acid metabolism, which is found to be lacking in PCOS patients. This systematic review and meta-analysis aimed to determine the effectiveness of LC supplementation for patients with PCOS.

Methods

We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Psychological Information Database (PsycINFO),

SUBMITTER: Mohd Shukri MF 

PROVIDER: S-EPMC9484467 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature