Accuracy of molecular diagnostic techniques in patients with a confirmed urine culture: A systematic review and meta-analysis.

ABSTRACT:

Introduction

We aimed to identify the molecular diagnostic techniques available for urinary tract infection (UTI) diagnosis and their accuracy compared to traditional urinary culture.

Methods

A systematic search was performed in MEDLINE (OVID), EMBASE, LILACS, and the Cochrane Central Register of Controlled Trials (CENTRAL). The populations were adult and pediatric patients with confirmed UTI by reference standard urine culture. The index test for the diagnosis of UTI was any molecular diagnostic technique. The primary outcome was the diagnosis of UTI with measures of sensitivity, specificity, positive and negative predictive values (PPV and NPV, respectively), positive likelihood ratio (LR+), negative likelihood ratio (LR-), diagnostic odds ratio (DOR), and area under the c

SUBMITTER: Robledo XG 

PROVIDER: S-EPMC9484739 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature