Reconstructing topography and extent of injury to the superior mesenteric artery plexus in right colectomy with extended D3 mesenterectomy: a composite multimodal 3-dimensional analysis.

ABSTRACT:

Background

Superior mesenteric artery plexus (SMAP) injury is reported to cause postoperative intractable diarrhea after pancreatic/colonic surgery with extended lymphadenectomy. This study aims to describe the SMAP microanatomy and extent of injury after right colectomy with extended D3 mesenterectomy for cancer.

Methods

Three groups (I) anatomical dissection, (II) postmortem histology, and (III) surgical specimen histology were included. Nerve count and area were compared between groups II and III and paravascular sheath thickness between groups I and II. 3D models were generated through 3D histology, nanoCT scanning, and finally through 3D printing.

Results

A total of 21 specimens were included as follows: Group (I): 5 (3 females, 80-93 years), the SMAP is a comple

SUBMITTER: Luzon JA 

PROVIDER: S-EPMC9485098 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature