Functional Impairment and Periodontitis in Rheumatoid Arthritis.

ABSTRACT:

Background

This study explored the association of functional impairment due to rheumatoid arthritis (RA) and RA disease activity with periodontal disease in patients with RA.

Methods

Ninety-three patients with RA were included. Their RA functional status was assessed using the Steinbrocker classification. The serum level of matrix metalloproteinase-3 (MMP-3) was used as an indicator of RA disease activity. Probing depth (PD) and clinical attachment level (CAL) were used as indicators of periodontal status. We examined the association of RA severity and MMP-3 levels with periodontal status using a generalised linear model (GLM).

Results

In a multivariate GLM, the coefficient for the mean PD was significantly positive in those with RA severity classes III or IV (referen

SUBMITTER: Hashimoto H 

PROVIDER: S-EPMC9485534 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature