Effects of maternal fructose intake on the offspring's kidneys.

ABSTRACT: Fructose overload is associated with cardiovascular and metabolic disorders. During pregnancy, these alterations may affect the maternal environment and predispose offspring to diseases.

Aims

To evaluate the renal morphology and function of offspring of dams that received fructose overload during pregnancy and lactation.

Methods

Female Wistar rats were divided into the control (C) and fructose (F) groups. C received food and water ad libitum, and F received food and d-fructose solution (20%) ad libitum. The d-fructose offer started 1 week before mating and continued during pregnancy and lactation. The progeny were designated as control (C) or fructose (F); after weaning, half of the F received water to drink (FW), and half received d-fructose (FF). Blood pressur

SUBMITTER: Argeri R 

PROVIDER: S-EPMC9485812 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature