Coevolutionary insights between promoters and transcription factors in the plant and animal kingdoms.

ABSTRACT: The divergence and continuous evolution of plants and animals contribute to ecological diversity. Promoters and transcription factors (TFs) are key determinants of gene regulation and transcription throughout life. However, the evolutionary trajectories and relationships of promoters and TFs are still poorly understood. Here, we conducted extensive analysis of large-scale multi-omics sequences in 420 animal species and 223 plant species spanning nearly a billion years of evolutionary history. Results showed that promoter GC-content and TF isoelectric points, as features/signatures that accompany long biological evolution, exhibited increasing growth in animal cells but a decreasing trend in plant cells. Furthermore, the evolutionary trajectories of promoter and TF signatures in the animal

SUBMITTER: Zhang JS 

PROVIDER: S-EPMC9486516 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature