Prognostic value of neutrophil-to-lymphocyte ratio (NLR) in penile cancer: A systematic review and meta-analysis.

ABSTRACT:

Background

Penile cancer is rare among male malignancies. Various biomarkers have been used to predict the prognosis of cancer, one of which is the neutrophil to lymphocyte ratio (NLR). Therefore, we conducted this systematic review and meta-analysis to evaluate the prognostic value of NLR in penile cancer.

Methods

This review was conducted following the PRISMA guideline. Several databases, including Scopus, Science-direct, and PubMed, were systematically searched. The primary outcomes were lymph node metastasis (LNM), cancer-specific survival (CSS), and overall survival (OS). All statistical analyses were processed using Review Manager (RevMan) version 5.4.

Results

A total of six retrospective studies were included in the analysis. The cut-off values of NLR in the in

SUBMITTER: Saputra HM 

PROVIDER: S-EPMC9486611 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature