ABO incompatible living donor liver transplant with antibody titer of 1:4: First case report from Pakistan.

ABSTRACT:

Introduction and importance

The most common reason for live liver donor rejection is ABO incompatibility. With breaching this incompatibility barrier, probably an additional 25%-35% of liver transplantation (LT) procedures would become possible. Also, ABOi-LT can be lifesaving in acute settings. Initially, ABOi-LT reported a poor prognosis secondary to antibody-mediated rejection (AMR) which is more common in ABOi allograft recipients. AMR may be avoided by desensitization. Various desensitization protocols are practiced globally, however, there is no consensus available on the optimal desensitization protocol for the ABOi-LT. The ABO-incompatible (ABOi) can expand the liver donor pool tremendously. We report the first case of ABO incompatible-liver transplantation (ABOi-LT) from P

SUBMITTER: Dogar AW 

PROVIDER: S-EPMC9486708 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature