Muscarinic receptors: from clinic to bench to clinic.

ABSTRACT: Efforts to target muscarinic acetylcholine receptors in the brain have been hampered by dose-limiting side effects. In a tour de force of team science, Brown and colleagues have designed a muscarinic agonist that has been optimized to possess properties that could position it to succeed where other agonists have failed.

SUBMITTER: Foster DJ 

PROVIDER: S-EPMC9486979 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature