Systematic literature review of topical local anaesthesia or analgesia to donor site wounds.

ABSTRACT:

Background

Topical local analgesic and anaesthetic agents have been used both pre- and immediately post-harvest on split-thickness skin graft (STSG) donor site wounds (DSW). There is no systematic review of their effectiveness in providing post-harvest analgesia, or of the possible toxic effects of systemic absorption. This study is designed to address the question of which agent, if any, is favoured over the others and whether there are any safety data regarding their use.

Methods

Systematic literature review of randomised controlled trials of topical agents applied to STSG DSWs, with a view to providing analgesia. Studies identified via search of Cochrane and EBSCO databases. No restrictions on language or publication year. Primary outcomes: pain at the time of (awake) STS

SUBMITTER: McBride CA 

PROVIDER: S-EPMC9486980 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature