Intimate partner violence and oral HIV pre-exposure prophylaxis adherence among young African women.

ABSTRACT:

Objective

To estimate the effect of intimate partner violence (IPV) on oral pre-exposure prophylaxis (PrEP) adherence among adolescent girls and young women (AGYW).

Design

We conducted a secondary analysis of data from HIV Prevention Trials Network 082 (HPTN 082), a multisite prospective study designed to assess oral PrEP adherence among AGYW in southern Africa.

Methods

We estimated the relative prevalence of high PrEP adherence 3 and 6 months after initiation among AGYW 16-25 years who reported a history of any IPV in the past year at enrollment versus AGYW who did not, both overall and by age. High adherence was defined as an intracellular tenofovir-diphosphate concentration at least 700 fmol/punch or more dried blood spots.

Results

Among 409 PrEP-initiating

SUBMITTER: Giovenco D 

PROVIDER: S-EPMC9486991 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature