PROFILEing idiopathic pulmonary fibrosis: rethinking biomarker discovery.

ABSTRACT: Despite major advances in the understanding of the pathogenesis of idiopathic pulmonary fibrosis (IPF), diagnosis and management of the condition continue to pose significant challenges. Clinical management of IPF remains unsatisfactory due to limited availability of effective drug therapies, a lack of accurate indicators of disease progression, and an absence of simple short-term measures of therapeutic response. The identification of more accurate predictors of prognosis and survival in IPF would facilitate counseling of patients and their families, aid communication among clinicians, and would guide optimal timing of referral for transplantation. Improvements in molecular techniques have led to the identification of new disease pathways and a more targeted approach to the development of

SUBMITTER: Maher TM 

PROVIDER: S-EPMC9487381 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature