Preoperative risk factors for early recurrence after resection of perihilar cholangiocarcinoma.

ABSTRACT:

Background

Early recurrence after curative resection of perihilar cholangiocarcinoma (PHCC) often occurs within a year of surgery. Preoperative predictors of early recurrence remain unclear. The aim of this study was to define reliable preoperative predictors of early recurrence.

Methods

Medical records and preoperative multidetector-row CT of patients with PHCC who underwent resection between 2002 and 2018 were reviewed. Clinical findings, tumour markers, and radiological appearances including a 'periductal enation sign' (PES) where there was evidence of soft tissue enhancement appearing to arise from the extrahepatic bile duct, were analysed.

Results

Among 261 patients who underwent resection for PHCC, 67 (25.7 per cent) developed early recurrence. Multivariable ana

SUBMITTER: Yamamoto R 

PROVIDER: S-EPMC9487653 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature